News & Features: USC molecular scientists lengthen life span of yeast by deleting SIR2 gene

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Topic: USC molecular scientists lengthen life span of yeast by deleting SIR2 gene

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posted 23. November 2005 23:20

Study Challenges View on Aging Research
17th November 2005

By Carl Marziali

Source : University of Southern California News Room

Paragraph 6:
Rather than adding copies of SIR2 to yeast, Longo’s research group deleted the gene altogether.

Paragraph 7:
The result was a dramatically extended life span – up to six times longer than normal – when the SIR2 deletion was combined with caloric restriction and/or a mutation^ in one or two genes, RAS2 and SCH9, that control the storage of nutrients and resistance to cell^ damage.

[Emphases added by ISCID News Editor]
[Link-underlined terms with ^ indicate linked entry in ISCID Encyclopedia of Science and Philosophy as added by ISCID News Editor]

Read the full story at USC News Room

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