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Author Topic: Polycomb proteins guide stem cell development
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Icon 1 posted 24. April 2006 07:16      Profile for ISCID News Editor   Email ISCID News Editor   Send New Private Message       Edit/Delete Post 
Source: MIT News Office
New map reveals secret of stem cell development
David Cameron, Whitehead Institute
April 21, 2006

First and Last Paragraphs
How humans manage to develop from a single fertilized egg into the trillions of cells that make up a mature adult remains a poorly understood process. Now, using both human and mouse embryonic stem cells, researchers from MIT, the Whitehead Institute and Harvard have mapped how a key developmental ingredient controls the genome.

"Polycomb is dynamic, working with other molecules to silence genes and then gradually allowing them to activate during development," Jaenisch said. "It is also the founding ingredient for development, so knowing how it works and which genes it interacts with will be invaluable for understanding these amazing cells."

[ 24. April 2006, 07:16: Message edited by: ISCID News Editor ]

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