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Author Topic: Expectations of evidence
yersinia
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Member # 324

Icon 1 posted 19. September 2002 02:07      Profile for yersinia     Send New Private Message       Edit/Delete Post 
This was spawned off of the immune system thread. I may only have time to post the beginning comments at the moment:

link

First, Mike Gene wrote,

quote:

Above, Dembski asked you to put your "hallmarks of evolution" on the table. You then listed three criteria. I found this encouraging. However, in light of your parsimony argument above, it's starting to look like your hallmarks have no teeth. Above, you seem to be arguing that you accept the evolution of the flagellum because of the evolution of blood clotting and the immune system. In other words, you don't need any hallmarks in the case of the flagellum. Instead, you appeal to philosophical arguments about parsimony.

As I see it, a rigorous hallmark would be used to score something as evolved or not. That is, biological features that fail to exhibit any of your hallmarks should not be scored as "evolved." But how can this be when the non-teleological approach begins by assuming every biotic feature arose through evolution? That is, since you already believe every biotic feature arose through evolution, and use parsimony arguments to justify extrapolating evolution here from evolution there, your hallmarks appear to be nothing more than window dressing that are applied, post-hoc, if they can be applied. Put simply, your hallmarks do not appear to have any scoring power since failure to find hallmarks does not dislodge or even weaken the evolution belief. It seems to me you are trying to draw from two different methodological approaches that don't mix very well - one approach scores and the other approach generalizes.

I do think the scoring approach is a better way to address a history full of contingency. Attempts to generalize end up smearing all biotic data into a blurry, homogenous whole, such that changing wing colors in moths becomes evidence for the Darwinian origin of the bacterial flagellum. I prefer the investigative method that scores; one that is open-ended, looking for the best explanation rather than merely looking for facts to support preconceptions. This is why your leading attempt to highlight hallmarks of flagellar evolution (motA-exbB homology) is much better than the philosophical arguments revolving around parsimony. That's why I will try to get to it in the next few busy days.

And I wrote,

quote:

Hey Mike,

I agree that it would be useful to formalize what we might call "relative likelihood reasoning" or some such thing, perhaps even with some attempt at scoring.

Perhaps it would be best to start another thread to do this. Briefly, several distinctions that would probably be useful in such an endeavor:

Positive evidence (evidence for some hypothesis) vs. negative evidence (evidence against some hypothesis), perhaps vs. "neutral" (e.g., perhaps no evidence either way).

Evidence for "it did happen this way" vs. evidence for "it could happen this way". E.g. the known Type III secretion systems, which are derived, are not particularly good evidence for "it did happen this way" but (IMO) are certainly evidence for "it could happen this way" ("it" = evolution of flagellum from a transport system).

A consideration of *expectation* of evidence, i.e. we can expect more evidence regarding the evolution of things that fossilize easily than we can for the evolution of things that fossilize poorly. E.g., chimps live in rainforests with acidic soils that dissolve bones so the lack of chimp fossils compared to hominid fossils is not particularly surprising.

(Along a similar vein, billions of years older = less expectation of evidence; this is an argument I advanced earlier regarding the flagellum vs. the immune system)

Another variation on the above would be length/amount of study. Short version that often causes woe to those of us interested in evolution: relevant to medicine = lots and lots of study (a plus in the case of the immune system, however); not relevant to medicine = take a hike. Bombadier beetles just aren't going to get quite the amount of attention that the immune system does.

There's probably more ("length of time since reasonably complete understanding of system"), but that's a start.

Obviously complete agreement might be difficult but perhaps it would be useful. Feel free to quote/use this in another thread if you are so inspired, Mike.

Thanks, nic

& Mike replied:

quote:

Nic,

The formulation of some kind of "relative likelihood reasoning" sounds interesting, but my main point dealt with the tension created by using both the "hallmark" approach and the "parsimony" approach. It would seem to me that attempts to converge these different methods into a single approach merely end up weakening both. For example, if you were to find sufficient evolutionary hallmarks for biotic feature X, the "hallmarks" end up as nothing more than window dressing given that you already believed X evolved on the basis of parsimony. But if you don't find any hallmarks for biotic feature Y, the appeal to parsimony ends up looking like a dive down the escape hatch (to rescue the pre-existing belief that Y evolved). Put simply, by bringing parsimony into the picture, your "hallmarks" end up looking more like apologetic devices than investigative tools. Personally, I'd jettison the "parsimony" appeals, as they tend to collapse into a philosophical argument and merely undercut your hallmarks.

This problem is then amplified when some of the qualifications as part of your "relative likelihood reasoning" are put into play. For example:

quote:
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Along a similar vein, billions of years older = less expectation of evidence; this is an argument I advanced earlier regarding the flagellum vs. the immune system
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Is this yet another apologetic move or a true investigative concern? It's hard to tell. If it is the latter, it would seem to me that non-teleologists should rigorously define some type of temporal evidential threshold, where we would not expect to find any evidence for evolution prior to this threshold. Then, appeals to ancient events would have some teeth. As it stands, the "it's too old" argument comes across as more of an excuse that gets applied in an "escape hatch" manner (creating now two escape hatches). But is the "it's too old" argument truly valid? Does it always apply? For example, which is older - the origin of mitochondria or the origin of Broca's speech center, avian lungs, and the bat's wing? It would seem to me that the evolutionary origin of the latter three, while much more recent than the origin of mitochondria, are less well "evidenced." Or, if we turn to the flagellum itself, recall that Ken Miller and many others argue the evolutionary origin of the Krebs cycle is well-evidenced. Yet the Krebs is found in both archaea and eubacteria (unlike eubacterial-specific flagellum we discuss), clearly indicating it to be older than the bacterial flagellum (from the traditional viewpoint, that is). If you can find evidence for the evolutionary origin of the Krebs, complaining that the evolutionary origin of the flagellum was too old clearly comes across as a rationalization and excuse.

Perhaps my perceptions are flawed here, but this is how this all ends up looking from where I sit:

You think the Krebs Cycle evolved and there is evidence of this evolution.

The Krebs Cycle is older than the bacterial flagellum.

We can't expect to find evidence for the evolutionary origin of the flagellum because it is too old.

Ah, but we have evidence for the evolutionary origin of the flagellum (i.e., ExbB-to be addressed soon).

Ah, but if we didn't have this evidence, we'd have to conclude the flagellum evolved because the immune system evolved.

Like I said before, I'll try to deal with your hallmark for the flagellum. In the meantime, it would be nice to see you explain why it is the capabilities of chance alone are very very limited.

Brief reply:

I expect that this kind of thing is why this has never been formalized (well, actually I bet it has somewhere, but it is probably very difficult to generalize). I tend to think MG is oversimplifying my position here; for example, there are not going to be any hard and fast lines, rather "probability of finding relevant evidence" is going to variously along several axis; here is my (current) list:

- time since event

- understanding of the system (never an all-or-nothing thing, but certain things are reasonably completely understood long before other things, e.g. the Krebs cycle was I think worked out quite awhile ago compared to the flagellum but I'm not up on my History of Biochemistry)

- fossilizability (flagellum, bird lungs, small flying critters in general = low; solid bony structures of common animals (e.g. herbivores are way more common than carnivores in any ecosystem, guess how few T rex skeletons we actually have?)

- understanding of developmental biology & developmental genetics (rapid advances here of late)

- understanding of phylogeny

- relative amount of extinct vs. surviving lineages in the relevant clade (evolutionary immunologists would kill to get some placoderms for instance)

- relative amount of study of these lineages (e.g., detailed immunological study of cephalochordates, surely an important piece of the puzzle, has only begun -- although in general a fair bit of research on deuterstome immunology has been done)

- same thing for sequencing. If we had complete genome sequences for all the basal deuterostomes we could be more confident in asserting the presence or absence of currently suspected-but-not-proven homologs. Without those genome sequences, current failure to find gene X proves almost zilch.

etc. It's quite a long list, I would encourage you to add your own.

Anyway, main point: the place to look for ID is not where most of the above factors point towards "low probability of evidence", but where most of them point towards "high probability of evidence". Only in "high probability of evidence" situations does the existence of gaps or lack of intermediates become an impressive argument.

As this is the main argument used for ID this is very important -- especially since everyone's favorite IDist, Behe, picked systems without fossil records, that are very ancient, etc. The two systems where the probability-of-evidence issues were less severe were blood clotting and the immune system, and those are the very systems ID is getting burned on right now over in the immune system thread.

nic

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Mike Gene
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Icon 1 posted 19. September 2002 08:00      Profile for Mike Gene     Send New Private Message       Edit/Delete Post 
Nic : Anyway, main point: the place to look for ID is not where most of the above factors point towards "low probability of evidence", but where most of them point towards "high probability of evidence". Only in "high probability of evidence" situations does the existence of gaps or lack of intermediates become an impressive argument.

I'd agree, but we also have to keep in mind the distinction between ontological and epistemological evidence, as explained on my web page. But for now, the main point, as I see it, is whether it is a good investigative idea to mix the "identify the hallmark and infer" method with the "parsimony mandates extrapolation" method. As I mentioned above, mixing both approaches ends up turning them both into apologetic devices.

Two more things. First, it seems clear to me that one is going to have to rely on intuition in trying to determine where and when the listed dynamics come into play (and to what degree they come into play). I'm encouraged to see that Nic is beginning to understand that intuition is more than something to be ridiculed. Secondly, a similar approach could likewise be developed for the expectations about the designer and ID. For example, those critical of ID demand that we must be able to watch the designer designing before anyone can take ID seriously. How reasonable is that?

[ 19 September 2002, 08:34: Message edited by: Mike Gene ]

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yersinia
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Icon 1 posted 19. September 2002 12:29      Profile for yersinia     Send New Private Message       Edit/Delete Post 
Hey Mike,

quote:

But for now, the main point, as I see it, is whether it is a good investigative idea to mix the "identify the hallmark and infer" method with the "parsimony mandates extrapolation" method. As I mentioned above, mixing both approaches ends up turning them both into apologetic devices.

I disagree. If the "high-probability of evidence" complex systems reveal evidence for originating via the process of evolution, then for the origin of "low-probability of evidence" complex systems it is much more parsimonious to think that similar processes accounted for their origin, than to conjure up an extra, very highly complex, unevidenced IDer to explain them.

quote:

Two more things. First, it seems clear to me that one is going to have to rely on intuition in trying to determine where and when the listed dynamics come into play (and to what degree they come into play). I'm encouraged to see that Nic is beginning to understand that intuition is more than something to be ridiculed.

I dunno if "intuition" is the right word; I would prefer to say that the list of considerations I mentioned are objective but difficult to quantify. In these situations the way things proceed is usually to rank cases, e.g. we can rank Behe's systems by time-since-origin (and indeed, "understanding of the evolutionary origin of the system" follows this ranking exactly)

quote:

Secondly, a similar approach could likewise be developed for the expectations about the designer and ID. For example, those critical of ID demand that we must be able to watch the designer designing before anyone can take ID seriously. How reasonable is that?

The reason "watch the designer" comes up is that it is one of the ways to develop a model for the designer which can then makes testable predictions about what should be observed in the historical data. There are other ways to do this -- but the favored method of ID, "point to gaps in low-probability-of-evidence situations" is not one of them.

nic

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Mike Gene
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Icon 1 posted 21. September 2002 14:00      Profile for Mike Gene     Send New Private Message       Edit/Delete Post 
Hi Nic,

You write: I disagree. If the "high-probability of evidence" complex systems reveal evidence for originating via the process of evolution, then for the origin of "low-probability of evidence" complex systems it is much more parsimonious to think that similar processes accounted for their origin, than to conjure up an extra, very highly complex, unevidenced IDer to explain them.

But if you are going use parsimony like this, you should first establish two things:

1. A robust, objective methodology of scoring something as "high-probability of evidence" vs. " low-probability of evidence." Without first accomplishing this, parsimony arguments come across as escape hatches, where it appears the primary motivation for scoring something as " low-probability of evidence" is because you don't have any evidence.

2. Since your extrapolation is essentially an argument from analogy, you should be clear that the two things being compared are truly analogous. For example, extrapolating the "high-probability of evidence" from Biston betularia evolution to the evolutionary origin of the eubacterial flagellar machine is not a very convincing use of "parsimony."

As it stands, you basically have an argument that proceeds as follows:

Hallmarks? Yes - infer evolution.
Hallmarks? Maybe - infer evolution.
Hallmarks? No - infer evolution.

Again, since you come to this whole issue with the pre-existing belief that EVERY biotic feature owes its origin to darwinian evolution, your attempt to employ hallmarks comes across as an apologetic move (i.e., reinforcing what you already believe). I'm not saying that it is, but it sure has this flavor to it.

I dunno if "intuition" is the right word; I would prefer to say that the list of considerations I mentioned are objective but difficult to quantify. In these situations the way things proceed is usually to rank cases, e.g. we can rank Behe's systems by time-since-origin (and indeed, "understanding of the evolutionary origin of the system" follows this ranking exactly)

Intuition is the right word here. Perhaps we should simply start applying these concepts to illustrate this. To start it off, when did the immune system evolve?

Let me also add two more criteria to your list:

The more frequent the role that cooption plays in the origin of a system, the more likely we should be able to uncover traces of that evolution.

The simpler the creature (ease of handling, shorter generation times, etc.), the easier it should be to artificially evolve analogs of the system in question.

What y'think?

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