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Atypical Hyperplasia

Hyperplasia is an increase in number of cells in an organ or tissue, causing it to increase in size, but by itself is not necessarily cancerous or even dangerous. Atypical hyperplasia, on the other hand, is an increase in the number of cells resulting in abnormal enlargement, or with the cells in the increase being atypical in some manner. This form of hyperplasia is often, though not always, cancerous.

Atypical hyperplasia can be triggered by increased demand for that tissue or organ; chronic inflammatory response; hormonal dysfunction; or neoplasia. Or it may be triggered by no obvious cause at all. Even if the atypical hyperplasia is not cancerous, it will increase your chances for getting cancer later.

Most atypical hyperplasia are triggered by a normal hyperplasia. For instance, amenorrhea or ologomenorrhea may result in thickening of the uterine endometrium, a hyperplasia. The increased production of cells makes it more likely that some will mutate into a cancer. In the endometrium, this indicates endometrial cancer. The longer endometriosis is left untreated, the more likely it will develop into cancer.

Web Resources On Atypical Hyperplasia

Definite breast cancer risks
Breast Cancer Care

Book Resources On Atypical Hyperplasia

Intimal Hyperplasia by Philip B. Dobrin (Ed)
Endometrial Hyperplasia: A Medical Dictionary, Bibliography, And Annotated Research Guide To Internet References by Icon Health Publications

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