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Autologous Lymphocyte

An autologous lymphocyte is a lymphocyte taken from a person's own white blood cells. These cells are separated from the rest of the blood and preserved for reimplantation in the cancer patient so that they can rebuild the immune system quickly and improve the patient's chances for a good recovery. In addition, lymphocytes sometimes can provide stem cells for autologous stem cell transplantation.

Similar to autologous lymphocyte transplantation is peripheral blood stem cell transplant or leukapheresis, in which the patient's blood is slowly removed. A machine sorts through the cells and removes only the immature cells, or stem cells; from these cells, all blood cell types may be developed. The rest of the blood is returned to the body.

Stem cells collected in this way are frozen. The patient undergoes procedures that typically destroy his body's ability to produce new blood cells, usually by destroying the bone marrow. The re-injection of autologous cells creates a new pool of stem cells in the bone marrow, from which the different cells of the blood may again be produced.

Web Resources On Autologous Lymphocyte

Role of autologous lymphocyte cytotoxicity in colonic neoplasia
Autologous Lymphocyte Infusion

Book Resources On Autologous Lymphocyte

Killer Lymphocytes by Gideon Berke & William R. Clark
Lymphocyte Development: Cell Selection Events and Signals During Immune Ontogeny by Shiv Pillai

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