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Phosphorylation

The biochemical process of adding a phosphate molecule to another organic molecule. It serves important regulatory functions in eukaryote cells, regulating proteins by attaching to certain amino acids along the polypeptide chain, changing protein fold configuration and/or changing the function of the protein in cell processes.

Phosphorylation is most commonly accomplished by enzymes called protein kinases. It is estimated that up to 30% of proteins and most cellular pathways - particularly those involved in signal transduction - are regulated by kinases, which account for approximately 2% of eukaryotic genes.

Web Resources On Phosphorylation

Tubulin Phosphorylation
Phosphorylation

Book Resources On Phosphorylation

Protein Phosphorylation in the Nervous System by Eric J. Nestler, Paul Greengard
The Enzymes: Control by Phosphorylation by Paul D. Boyer, Edwin G. Krebs

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