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Synapse A synapse is a specialized junction between neurons that receive chemical or electrical signals [neurotransmitters] released by dendritic spines, across a gap called a "synaptic cleft." When a neuron receives action potential it travels down the axon to its end [axon terminal] to signal the release of neurotransmitters stored in vesicles there, to be transmitted by diffusion across the synaptic cleft to a neighboring neuron. The action potential produces calcium ions that enter the neuron through calcium channels on the membrane, and these ions trigger the biochemical cascade which triggers release of specific neurotransmitters. The released neurotransmitters bind to receptors on the membrane of the neighboring neuron, and these change voltage at the receptor sites to transmit the action potential. Oxford Companion to the Mind by O.L. Zangwill (Author), Richard L. Gregory (Ed.). |
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